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A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are an important family of natural products. Their biosynthesis follows a common scheme in which the leader peptide of a precursor peptide guides the modifications of a single core peptide. Here we describe biochemical studie...

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Publicat a:Nat Commun
Autors principals: Zhang, Yi, Li, Kunhua, Yang, Guang, McBride, Joshua L., Bruner, Steven D., Ding, Yousong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934393/
https://ncbi.nlm.nih.gov/pubmed/29725007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04154-3
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