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Cellular and Molecular Mechanisms Underlying Planar Cell Polarity Pathway Contributions to Cancer Malignancy

While the mutational activation of oncogenes drives tumor initiation and growth by promoting cellular transformation and proliferation, increasing evidence suggests that the subsequent re-engagement of largely dormant developmental pathways contributes to cellular phenotypes associated with the mali...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: VanderVorst, Kacey, Hatakeyama, Jason, Berg, Anastasia, Lee, Hyun, Carraway, Kermit L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934344/
https://ncbi.nlm.nih.gov/pubmed/29107170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2017.09.026
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