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Activation of G(αq) signaling enhances memory consolidation and slows cognitive decline

Perhaps the most devastating decline with age is the loss of memory. Therefore, identifying mechanisms to restore memory function with age is critical. Using C. elegans associative learning and memory assays, we identified a gain-of-function G(αq) signaling pathway mutant that forms a long-term (CRE...

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Publicat a:Neuron
Autors principals: Arey, Rachel N., Stein, Geneva M., Kaletsky, Rachel, Kauffman, Amanda, Murphy, Coleen T.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934306/
https://ncbi.nlm.nih.gov/pubmed/29656871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.039
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