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Activation of G(αq) signaling enhances memory consolidation and slows cognitive decline

Perhaps the most devastating decline with age is the loss of memory. Therefore, identifying mechanisms to restore memory function with age is critical. Using C. elegans associative learning and memory assays, we identified a gain-of-function G(αq) signaling pathway mutant that forms a long-term (CRE...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Arey, Rachel N., Stein, Geneva M., Kaletsky, Rachel, Kauffman, Amanda, Murphy, Coleen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934306/
https://ncbi.nlm.nih.gov/pubmed/29656871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.039
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