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Activation of G(αq) signaling enhances memory consolidation and slows cognitive decline

Perhaps the most devastating decline with age is the loss of memory. Therefore, identifying mechanisms to restore memory function with age is critical. Using C. elegans associative learning and memory assays, we identified a gain-of-function G(αq) signaling pathway mutant that forms a long-term (CRE...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Arey, Rachel N., Stein, Geneva M., Kaletsky, Rachel, Kauffman, Amanda, Murphy, Coleen T.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934306/
https://ncbi.nlm.nih.gov/pubmed/29656871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.039
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