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DNA methylation of the BRD2 promoter is associated with Juvenile Myoclonic Epilepsy in Caucasians

OBJECTIVE: Juvenile Myoclonic Epilepsy (JME) is a common adolescent-onset genetic generalized epilepsy (GGE) syndrome. Multiple linkage and association studies have found that BRD2 influences the expression of JME. The BRD2-JME connection is further corroborated by our murine model: Brd2 haplo-insuf...

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Bibliografiska uppgifter
I publikationen:Epilepsia
Huvudupphovsmän: Pathak, Shilpa, Miller, James, Morris, Emily C, Stewart, William C L, Greenberg, David A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934302/
https://ncbi.nlm.nih.gov/pubmed/29608786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14058
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