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Altered expression of the FMR1 splicing variants landscape in premutation carriers

FMR1 premutation carriers (55–200 CGG repeats) are at risk for developing Fragile X-associated Tremor/Ataxia Syndrome (FXTAS), an adult onset neurodegenerative disorder. Approximately 20% of female carriers will develop Fragile X-associated Primary Ovarian Insufficiency (FXPOI), in addition to a num...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta
Glavni autori: Tseng, Elizabeth, Tang, Hiu-Tung, AlOlaby, Reem Rafik, Hickey, Luke, Tassone, Flora
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933929/
https://ncbi.nlm.nih.gov/pubmed/28888471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2017.08.007
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