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A streamlined method for transposon mutagenesis of Rickettsia parkeri yields numerous mutations that impact infection

The rickettsiae are obligate intracellular alphaproteobacteria that exhibit a complex infectious life cycle in both arthropod and mammalian hosts. As obligate intracellular bacteria, rickettsiae are highly adapted to living inside a variety of host cells, including vascular endothelial cells during...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lamason, Rebecca L., Kafai, Natasha M., Welch, Matthew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933787/
https://ncbi.nlm.nih.gov/pubmed/29723287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197012
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