Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models

The LSL-Kras(G12D/+); LSL-Trp53(R172H/+); Pdx-1-Cre (KPC) mouse model represents an established and frequently used transgenic model to evaluate novel therapies in pancreatic cancer. Tumor onset is variable in the KPC model between 8 weeks and several months. Therefore, non-invasive imaging tools ar...

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Vydáno v:J Vis Exp
Hlavní autoři: Goetze, Robert-Guenther, Buchholz, Soeren M., Patil, Shilpa, Petzold, Golo, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933419/
https://ncbi.nlm.nih.gov/pubmed/29683461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56979
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