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A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

Research on cardiac hypertrophy and heart failure is frequently based on pressure overload mouse models induced by TAC. The standard procedure is to perform a partial thoracotomy to visualize the transverse aortic arch. However, the surgical trauma caused by the thoracotomy in open-chest models chan...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Eichhorn, Lars, Weisheit, Christina Katharina, Gestrich, Christopher, Peukert, Konrad, Duerr, Georg Daniel, Ayub, Muhammad Ajmal, Erdfelder, Felix, Stöckigt, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933408/
https://ncbi.nlm.nih.gov/pubmed/29683463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57397
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