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A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

Research on cardiac hypertrophy and heart failure is frequently based on pressure overload mouse models induced by TAC. The standard procedure is to perform a partial thoracotomy to visualize the transverse aortic arch. However, the surgical trauma caused by the thoracotomy in open-chest models chan...

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Bibliografische gegevens
Gepubliceerd in:J Vis Exp
Hoofdauteurs: Eichhorn, Lars, Weisheit, Christina Katharina, Gestrich, Christopher, Peukert, Konrad, Duerr, Georg Daniel, Ayub, Muhammad Ajmal, Erdfelder, Felix, Stöckigt, Florian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933408/
https://ncbi.nlm.nih.gov/pubmed/29683463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57397
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