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Aortic Remodeling Following Transverse Aortic Constriction in Mice is Attenuated with AT(1) Receptor Blockade

OBJECTIVE: Although hypertension is the most common risk factor for thoracic aortic diseases, it is not understood how increased pressures on the ascending aorta lead to aortic aneurysms. We investigated the role of Ang II type 1 (AT(1)) receptor activation in ascending aortic remodeling in response...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Kuang, Shao-Qing, Geng, Liang, Prakash, Siddharth K., Cao, Jiu-Mei, Guo, Steven, Villamizar, Carlos, Kwartler, Callie S., Ju, Xiaoxi, Brasier, Allan R., Milewicz, Dianna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154247/
https://ncbi.nlm.nih.gov/pubmed/23868934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301624
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