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Aortic Remodeling Following Transverse Aortic Constriction in Mice is Attenuated with AT(1) Receptor Blockade

OBJECTIVE: Although hypertension is the most common risk factor for thoracic aortic diseases, it is not understood how increased pressures on the ascending aorta lead to aortic aneurysms. We investigated the role of Ang II type 1 (AT(1)) receptor activation in ascending aortic remodeling in response...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Kuang, Shao-Qing, Geng, Liang, Prakash, Siddharth K., Cao, Jiu-Mei, Guo, Steven, Villamizar, Carlos, Kwartler, Callie S., Ju, Xiaoxi, Brasier, Allan R., Milewicz, Dianna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154247/
https://ncbi.nlm.nih.gov/pubmed/23868934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301624
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