17β-Estradiol Regulates Microglia Activation and Polarization in the Hippocampus Following Global Cerebral Ischemia

17β-Estradiol (E2) is a well-known neuroprotective hormone, but its role in regulation of neuroinflammation is less understood. Recently, our lab demonstrated that E2 could regulate the NLRP3 (NOD-like receptor protein 3) inflammasome pathway in the hippocampus following global cerebral ischemia (GC...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Thakkar, Roshni, Wang, Ruimin, Wang, Jing, Vadlamudi, Ratna K., Brann, Darrell W.
Format: Artigo
Language:Inglês
Published: Hindawi 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932444/
https://ncbi.nlm.nih.gov/pubmed/29849895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4248526
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