NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17β-Estradiol

17β-Estradiol (E2) is a well-known neuroprotective factor in the brain. Recently, our lab demonstrated that the neuroprotective and cognitive effects of E2 require mediation by the estrogen receptor (ER) coregulator protein and proline-, glutamic acid-, and leucine-rich protein 1 (PELP1). In the cur...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Thakkar, Roshni, Wang, Ruimin, Sareddy, Gangadhara, Wang, Jing, Thiruvaiyaru, Dharma, Vadlamudi, Ratna, Zhang, Quanguang, Brann, Darrell
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097821/
https://ncbi.nlm.nih.gov/pubmed/27843532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8309031
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