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The Interplay of Rogue and Clustered Ryanodine Receptors Regulates Ca(2+) Waves in Cardiac Myocytes
Ca(2+) waves in cardiac myocytes can lead to arrhythmias owing to delayed after-depolarisations. Based on Ca(2+) regulation from the junctional sarcoplasmic reticulum (JSR), a mathematical model was developed to investigate the interplay of clustered and rogue RyRs on Ca(2+) waves. The model success...
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| Udgivet i: | Front Physiol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932313/ https://ncbi.nlm.nih.gov/pubmed/29755362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00393 |
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