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The Interplay of Rogue and Clustered Ryanodine Receptors Regulates Ca(2+) Waves in Cardiac Myocytes

Ca(2+) waves in cardiac myocytes can lead to arrhythmias owing to delayed after-depolarisations. Based on Ca(2+) regulation from the junctional sarcoplasmic reticulum (JSR), a mathematical model was developed to investigate the interplay of clustered and rogue RyRs on Ca(2+) waves. The model success...

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Bibliografski detalji
Izdano u:Front Physiol
Glavni autori: Chen, Xudong, Feng, Yundi, Huo, Yunlong, Tan, Wenchang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932313/
https://ncbi.nlm.nih.gov/pubmed/29755362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00393
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