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Systematic evaluation of immobilized trypsin based fast protein digestion for deep and high-throughput bottom-up proteomics

Immobilized trypsin (IM) has been recognized as an alternative to free trypsin (FT) for accelerating protein digestion 30 years ago. However, some questions of IM still need to be answered. How does the solid matrix of IM influence its preference for protein cleavage and how well can IM perform for...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Shen, Xiaojing, Sun, Liangliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932237/
https://ncbi.nlm.nih.gov/pubmed/29577644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700432
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