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Strong cation exchange-reversed phase liquid chromatography-capillary zone electrophoresis-tandem mass spectrometry platform with high peak capacity for deep bottom-up proteomics

Two-dimensional (2D) liquid chromatography (LC)-tandem mass spectrometry (MS/MS) are typically employed for deep bottom-up proteomics, and the state-of-the-art 2D-LC-MS/MS has approached over 8,000 protein identifications (IDs) from mammalian cell lines or tissues in 1–3 days of mass spectrometer ti...

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Detalhes bibliográficos
Publicado no:Anal Chim Acta
Main Authors: Chen, Daoyang, Shen, Xiaojing, Sun, Liangliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831384/
https://ncbi.nlm.nih.gov/pubmed/29475469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2018.01.037
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