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Dissociable influences of APOE ε4 and polygenic risk of AD dementia on amyloid and cognition
OBJECTIVE: To investigate the effects of genetic risk of Alzheimer disease (AD) dementia in the context of β-amyloid (Aβ) accumulation. METHODS: We analyzed data from 702 participants (221 clinically normal, 367 with mild cognitive impairment, and 114 with AD dementia) with genetic data and florbeta...
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Pubblicato in: | Neurology |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Lippincott Williams & Wilkins
2018
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931806/ https://ncbi.nlm.nih.gov/pubmed/29592889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005415 |
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