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Validating the concept of mutational signatures with isogenic cell models
The diversity of somatic mutations in human cancers can be decomposed into individual mutational signatures, patterns of mutagenesis that arise because of DNA damage and DNA repair processes that have occurred in cells as they evolved towards malignancy. Correlations between mutational signatures an...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931590/ https://ncbi.nlm.nih.gov/pubmed/29717121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04052-8 |
| Oznake: |
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