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Cell Cycle Regulation by Alternative Polyadenylation of CCND1

Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown. CCND1 is a proto-oncogene that regulates progression through the G1-S phase of the cell cycle; moreover, it has been observed to be switching to pro...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wang, Qiong, He, Guopei, Hou, Mengmeng, Chen, Liutao, Chen, Shangwu, Xu, Anlong, Fu, Yonggui
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931507/
https://ncbi.nlm.nih.gov/pubmed/29717174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25141-0
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