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Cell Cycle Regulation by Alternative Polyadenylation of CCND1

Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown. CCND1 is a proto-oncogene that regulates progression through the G1-S phase of the cell cycle; moreover, it has been observed to be switching to pro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Qiong, He, Guopei, Hou, Mengmeng, Chen, Liutao, Chen, Shangwu, Xu, Anlong, Fu, Yonggui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931507/
https://ncbi.nlm.nih.gov/pubmed/29717174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25141-0
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