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An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers

Blood-brain barrier (BBB) is a specialized barrier that protects the brain microenvironment from toxins and pathogens in the circulation and maintains brain homeostasis. The principal sites of the barrier are endothelial cells of the brain capillaries whose barrier function results from tight interc...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Devraj, Kavi, Guérit, Sylvaine, Macas, Jakranka, Reiss, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931381/
https://ncbi.nlm.nih.gov/pubmed/29553506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57038
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