A shift from papillary to reticular fibroblasts enables tumour–stroma interaction and invasion

BACKGROUND: Tumour stroma consists of a heterogeneous population of fibroblasts and related mesenchymal cells, collectively dubbed cancer-associated fibroblasts (CAFs). These CAFs are key players in cancer invasion of cutaneous squamous cell carcinoma (SCC). As we have shown earlier, papillary and r...

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Pubblicato in:Br J Cancer
Autori principali: Hogervorst, Marieke, Rietveld, Marion, de Gruijl, Frank, El Ghalbzouri, Abdoelwaheb
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931114/
https://ncbi.nlm.nih.gov/pubmed/29551776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0024-y
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