A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions

BACKGROUND: Adult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34(+) bone marrow stem cells can be propagated in culture to autonomously express embryonic stem cell genes and embryonic germ layer lineage genes. The current study was...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Makar, Tapas, Nimmagadda, Vamshi K., Guda, Poornachander R., Hampton, Brian, Huang, Weiliang, Kane, Maureen A., Fishman, Paul S., Pessac, Bernard, Bever, Christopher T., Trisler, David
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930965/
https://ncbi.nlm.nih.gov/pubmed/29720239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0858-5
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