Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

BACKGROUND: Ovarian cancer is the most lethal gynaecological malignancy. Chemotherapy is the main stay of treatment for metastatic disease, with modest response rates but significant side effects. Therefore, there is a need for alternative therapies that can control the disease while offering good q...

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Publicado en:Cancer Cell Int
Autores principales: Chan, Karen K. L., Siu, Michelle K. Y., Jiang, Yu-xin, Wang, Jing-jing, Leung, Thomas H. Y., Ngan, Hextan Y. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930957/
https://ncbi.nlm.nih.gov/pubmed/29743815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0559-2
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