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Prenatal diagnosis in a hereditary Peutz-Jeghers syndrome family with high cancer risk

BACKGROUND: Peutz-Jeghers Syndrome (PJS) is a hereditary cancer predisposing syndrome caused by autosomal dominant mutations in the serine/threonine kinase 11 (STK11) gene and is associated with decreased life expectancy. Many families experience a poorer quality of life due to the psychological bur...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Wang, Zhiqing, Liu, Shu, Liu, Siping, Wang, Yadong, Chen, Junsheng, Wu, Baoping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930790/
https://ncbi.nlm.nih.gov/pubmed/29720104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-018-0594-9
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