PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. However, the precise mechanism of action of PCNP in the process of tumor growth has not yet been fully elucidated. METHODS: ShRNA knockdown and overexpression of PCNP wer...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMC Cancer
المؤلفون الرئيسيون: Wu, Dong-Dong, Gao, Ying-Ran, Li, Tao, Wang, Da-Yong, Lu, Dan, Liu, Shi-Yu, Hong, Ya, Ning, Hui-Bin, Liu, Jun-Ping, Shang, Jia, Shi, Jun-Feng, Wei, Jian-She, Ji, Xin-Ying
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2018
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930684/
https://ncbi.nlm.nih.gov/pubmed/29716528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4391-9
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