PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. However, the precise mechanism of action of PCNP in the process of tumor growth has not yet been fully elucidated. METHODS: ShRNA knockdown and overexpression of PCNP wer...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Wu, Dong-Dong, Gao, Ying-Ran, Li, Tao, Wang, Da-Yong, Lu, Dan, Liu, Shi-Yu, Hong, Ya, Ning, Hui-Bin, Liu, Jun-Ping, Shang, Jia, Shi, Jun-Feng, Wei, Jian-She, Ji, Xin-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930684/
https://ncbi.nlm.nih.gov/pubmed/29716528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4391-9
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