PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. However, the precise mechanism of action of PCNP in the process of tumor growth has not yet been fully elucidated. METHODS: ShRNA knockdown and overexpression of PCNP wer...

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Publicat a:BMC Cancer
Autors principals: Wu, Dong-Dong, Gao, Ying-Ran, Li, Tao, Wang, Da-Yong, Lu, Dan, Liu, Shi-Yu, Hong, Ya, Ning, Hui-Bin, Liu, Jun-Ping, Shang, Jia, Shi, Jun-Feng, Wei, Jian-She, Ji, Xin-Ying
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930684/
https://ncbi.nlm.nih.gov/pubmed/29716528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4391-9
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