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Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein–Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis

The biosynthesis of small-size polyene macrolides is ultimately controlled by a couple of transcriptional regulators that act in a hierarchical way. A Streptomyces antibiotic regulatory protein–large ATP-binding regulator of the LuxR family (SARP-LAL) regulator binds the promoter of a PAS-LuxR regul...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Barreales, Eva G., Vicente, Cláudia M., de Pedro, Antonio, Santos-Aberturas, Javier, Aparicio, Jesús F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930380/
https://ncbi.nlm.nih.gov/pubmed/29500267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00246-18
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