Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing

Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct therapy for Ebola virus disease (EVD) during the 2...

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Publicat a:mBio
Autors principals: Shrivastava-Ranjan, Punya, Flint, Mike, Bergeron, Éric, McElroy, Anita K., Chatterjee, Payel, Albariño, César G., Nichol, Stuart T., Spiropoulou, Christina F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930306/
https://ncbi.nlm.nih.gov/pubmed/29717011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00660-18
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