Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System

Induced pluripotent stem cell (iPSC)-derived T cells may provide future therapies for cancer patients, but those generated by current methods, such as the OP9/DLL1 system, have shown abnormalities that pose major barriers for clinical translation. Our data indicate that these iPSC-derived CD8 single...

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Опубликовано в: :Cell Rep
Главные авторы: Vizcardo, Raul, Klemen, Nicholas D., Islam, S.M. Rafiqul, Gurusamy, Devikala, Tamaoki, Naritaka, Yamada, Daisuke, Koseki, Haruhiko, Kidder, Benjamin L., Yu, Zhiya, Jia, Li, Henning, Amanda N., Good, Meghan L., Bosch-Marce, Marta, Maeda, Takuya, Liu, Chengyu, Abdullaev, Zied, Pack, Svetlana, Palmer, Douglas C., Stroncek, David F., Ito, Fumito, Flomerfelt, Francis A., Kruhlak, Michael J., Restifo, Nicholas P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930030/
https://ncbi.nlm.nih.gov/pubmed/29562175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.087
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