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Optimal dynamic control approach in a multi-objective therapeutic scenario: Application to drug delivery in the treatment of prostate cancer

Numerous problems encountered in computational biology can be formulated as optimization problems. In this context, optimization of drug release characteristics or dosing schedules for anticancer agents has become a prominent area not only for the development of new drugs, but also for established d...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Irurzun-Arana, Itziar, Janda, Alvaro, Ardanza-Trevijano, Sergio, Trocóniz, Iñaki F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929575/
https://ncbi.nlm.nih.gov/pubmed/29672523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006087
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