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Optimal dynamic control approach in a multi-objective therapeutic scenario: Application to drug delivery in the treatment of prostate cancer

Numerous problems encountered in computational biology can be formulated as optimization problems. In this context, optimization of drug release characteristics or dosing schedules for anticancer agents has become a prominent area not only for the development of new drugs, but also for established d...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Irurzun-Arana, Itziar, Janda, Alvaro, Ardanza-Trevijano, Sergio, Trocóniz, Iñaki F.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929575/
https://ncbi.nlm.nih.gov/pubmed/29672523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006087
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