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Remote Control of Mammalian Cells with Heat-Triggered Gene Switches and Photothermal Pulse Trains

Engineered T cells are transforming broad fields in biomedicine, yet our ability to control cellular activity at specific anatomical sites remains limited. Here we engineer thermal gene switches to allow spatial and remote control of transcriptional activity using pulses of heat. These gene switches...

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Bibliografski detalji
Izdano u:ACS Synth Biol
Glavni autori: Miller, Ian C., Castro, Marielena Gamboa, Maenza, Joe, Weis, Jason P., Kwong, Gabriel A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929470/
https://ncbi.nlm.nih.gov/pubmed/29579381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00455
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