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Remote Control of Mammalian Cells with Heat-Triggered Gene Switches and Photothermal Pulse Trains

Engineered T cells are transforming broad fields in biomedicine, yet our ability to control cellular activity at specific anatomical sites remains limited. Here we engineer thermal gene switches to allow spatial and remote control of transcriptional activity using pulses of heat. These gene switches...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Miller, Ian C., Castro, Marielena Gamboa, Maenza, Joe, Weis, Jason P., Kwong, Gabriel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929470/
https://ncbi.nlm.nih.gov/pubmed/29579381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00455
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