Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer

OBJECTIVES: We aimed to examine the association between homologous recombination repair (HRR)-related gene mutations and efficacy of oxaliplatin-based chemotherapy in patients with pancreatic ductal adenocarcinoma (PDAC). RESULTS: Non-synonymous mutations in HRR-related genes were found in 13 patien...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kondo, Tomohiro, Kanai, Masashi, Kou, Tadayuki, Sakuma, Tomohiro, Mochizuki, Hiroaki, Kamada, Mayumi, Nakatsui, Masahiko, Uza, Norimitsu, Kodama, Yuzo, Masui, Toshihiko, Takaori, Kyoichi, Matsumoto, Shigemi, Miyake, Hidehiko, Okuno, Yasushi, Muto, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929428/
https://ncbi.nlm.nih.gov/pubmed/29731985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24865
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