Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis

Accurate chromosome segregation is dependent on the spindle assembly checkpoint (SAC). In current models, the key direct role of Aurora B in the SAC has been suggested to be to promote rapid kinetochore localisation of MPS1, allowing MPS1 to generate the checkpoint signal. However, Aurora B is also...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Gurden, Mark D., Anderhub, Simon J., Faisal, Amir, Linardopoulos, Spiros
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929406/
https://ncbi.nlm.nih.gov/pubmed/29731963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10657
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