CM-101: Type I Collagen–targeted MR Imaging Probe for Detection of Liver Fibrosis

PURPOSE: To evaluate the biodistribution, metabolism, and pharmacokinetics of a new type I collagen–targeted magnetic resonance (MR) probe, CM-101, and to assess its ability to help quantify liver fibrosis in animal models. MATERIALS AND METHODS: Biodistribution, pharmacokinetics, and stability of C...

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Veröffentlicht in:Radiology
Hauptverfasser: Farrar, Christian T., Gale, Eric M., Kennan, Richard, Ramsay, Ian, Masia, Ricard, Arora, Gunisha, Looby, Kailyn, Wei, Lan, Kalpathy-Cramer, Jayashree, Bunzel, Michelle M., Zhang, Chunlian, Zhu, Yonghua, Akiyama, Taro E., Klimas, Michael, Pinto, Shirly, Diyabalanage, Himashinie, Tanabe, Kenneth K., Humblet, Valerie, Fuchs, Bryan C., Caravan, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Radiological Society of North America 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929363/
https://ncbi.nlm.nih.gov/pubmed/29156148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2017170595
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