SETD7 drives cardiac lineage commitment through stage-specific transcriptional activation

Cardiac development requires coordinated and large-scale rearrangements of the epigenome. The roles and precise mechanisms through which specific epigenetic modifying enzymes control cardiac lineage specification, however, remain unclear. Here we show the H3K4 methyltransferase SETD7 controls cardia...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Lee, Jaecheol, Shao, Ning-Yi, Paik, David T., Wu, Haodi, Guo, Hongchao, Termglinchan, Vittavat, Churko, Jared, Kim, Youngkyun, Kitani, Tomoya, Zhao, Ming-Tao, Zhang, Yue, Wilson, Kitchener D., Karakikes, Ioannis, Snyder, Michael P., Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929163/
https://ncbi.nlm.nih.gov/pubmed/29499155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.02.005
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