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ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20

Zscan4 is an early embryonic gene cluster expressed in mouse embryonic stem and induced pluripotent stem cells where it plays critical roles in genomic stability, telomere maintenance, and pluripotency. Zscan4 expression is transient, and characterized by infrequent high expression peaks that are qu...

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Detaylı Bibliyografya
Yayımlandı:Biochem Biophys Res Commun
Asıl Yazarlar: Portney, Benjamin A., Khatri, Raju, Meltzer, W. Alex, Mariano, Jennifer M., Zalzman, Michal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928792/
https://ncbi.nlm.nih.gov/pubmed/29477841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.02.155
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