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ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20

Zscan4 is an early embryonic gene cluster expressed in mouse embryonic stem and induced pluripotent stem cells where it plays critical roles in genomic stability, telomere maintenance, and pluripotency. Zscan4 expression is transient, and characterized by infrequent high expression peaks that are qu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Biophys Res Commun
Egile Nagusiak: Portney, Benjamin A., Khatri, Raju, Meltzer, W. Alex, Mariano, Jennifer M., Zalzman, Michal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928792/
https://ncbi.nlm.nih.gov/pubmed/29477841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.02.155
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