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Transforming Growth Factor β1 Suppresses the Type I Interferon Response and Induces Mitochondrial Dysfunction in Alveolar Macrophages()

Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with an established role in fibrosis; however, the immunosuppressive effects of TGFβ1 are less characterized. Elevated levels of TGFβ1 are found in patients with acute and chronic lung diseases, and the underlying disease processes are...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Grunwell, Jocelyn R., Yeligar, Samantha M., Stephenson, Susan, Ping, Xiao Du, Gauthier, Theresa W., Fitzpatrick, Anne M., Brown, Lou Ann S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928790/
https://ncbi.nlm.nih.gov/pubmed/29427413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701325
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