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Dexmedetomidine attenuates H(2)O(2)-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways

Dexmedetomidine (DEX), an α2 adrenoceptor agonist, has sedative and analgesic properties and myocardial protective effects. However, the mechanism underlying the protective effects of DEX on the myocardium remain unclear. The present study aimed to determine whether DEX serves an important role on c...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Liu, Xue-Ru, Li, Tao, Cao, Lu, Yu, Yi-Yan, Chen, Lin-Lin, Fan, Xue-Hui, Yang, Bin-Bin, Tan, Xiao-Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928682/
https://ncbi.nlm.nih.gov/pubmed/29568958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8751
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