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High expression of active ATF6 aggravates endoplasmic reticulum stress-induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway

Activating transcription factor 6 (ATF6), one of three sensor proteins in the endoplasmic reticulum (ER), is an important regulatory factor in the ER stress-induced apoptosis pathway. Although recent studies have made some progress in elucidating the regulation mechanism of ATF6, the specific regula...

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Détails bibliographiques
Publié dans:Mol Med Rep
Auteurs principaux: Huang, Jingyong, Wan, Li, Lu, Heping, Li, Xiaoqiang
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928631/
https://ncbi.nlm.nih.gov/pubmed/29512699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8658
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