Extract Enriched in Flavan-3-ols and Mainly Procyanidin Dimers Improves Metabolic Alterations in a Mouse Model of Obesity-Related Disorders Partially via Estrogen Receptor Alpha

Red wine polyphenol extracts improve cardiovascular and metabolic disorders linked to obesity. Their vascular protection is mediated by the activation of the alpha isoform of the estrogen receptor (ERα). In the present study, we explored the effects of a grape seed extract (GSE) enriched in the flav...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Leonetti, Daniela, Soleti, Raffaella, Clere, Nicolas, Vergori, Luisa, Jacques, Caroline, Duluc, Lucie, Dourguia, Catherine, Martínez, Maria C., Andriantsitohaina, Ramaroson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928481/
https://ncbi.nlm.nih.gov/pubmed/29740325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00406
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