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Inhibition of fucosylation in human invasive ductal carcinoma reduces E‐selectin ligand expression, cell proliferation, and ERK1/2 and p38 MAPK activation
Breast cancer tissue overexpresses fucosylated glycans, such as sialyl‐Lewis X/A (sLe(X) (/A)), and α‐1,3/4‐fucosyltransferases (FUTs) in relation to increased disease progression and metastasis. These glycans in tumor circulating cells mediate binding to vascular E‐selectin, initiating tumor extrav...
Shranjeno v:
| izdano v: | Mol Oncol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5928367/ https://ncbi.nlm.nih.gov/pubmed/29215790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12163 |
| Oznake: |
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