Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription

Macrodomains are conserved protein folds associated with ADP-ribose binding and turnover. ADP-ribosylation is a posttranslational modification catalyzed primarily by ARTD (aka PARP) enzymes in cells. ARTDs transfer either single or multiple ADP-ribose units to substrates, resulting in mono- or poly-...

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Publicado no:Sci Rep
Main Authors: Bütepage, Mareike, Preisinger, Christian, von Kriegsheim, Alexander, Scheufen, Anja, Lausberg, Eva, Li, Jinyu, Kappes, Ferdinand, Feederle, Regina, Ernst, Sabrina, Eckei, Laura, Krieg, Sarah, Müller-Newen, Gerhard, Rossetti, Giulia, Feijs, Karla L. H., Verheugd, Patricia, Lüscher, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928194/
https://ncbi.nlm.nih.gov/pubmed/29712969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25137-w
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