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G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old
Frailty is characterized by a decline in physiological reserve and increased vulnerability. Previous studies have shown that KLOTHO (KL) plays a protective role in several age-related diseases. We hypothesize a probable protective effect of KL on frailty in the elderly population and included a coho...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5928057/ https://ncbi.nlm.nih.gov/pubmed/29712948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25040-4 |
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