A Sensitive and Rapid Ultra High-Performance Liquid Chromatography with Tandem Mass Spectrometric Assay for the Simultaneous Quantitation of Cyclophosphamide and the 4-Hydroxycyclophosphamide Metabolite in Human Plasma

Analysis of cyclophosphamide (CP) and its metabolite, 4-hydroxycyclophosphamide (4OHCP), in a single assay has the ability to improve sampling techniques benefitting both the patients who are receiving the drug and the clinicians drawing samples. Due to instability in plasma (t(1/2) = 4 minutes), im...

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Udgivet i:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Hall, O. Morgan, Peer, Cody J., Fitzhugh, Courtney D., Figg, William D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927828/
https://ncbi.nlm.nih.gov/pubmed/29656084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2018.04.016
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