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All-atom molecular dynamics of the HBV capsid reveals insights into biological function and cryo-EM resolution limits

The hepatitis B virus capsid represents a promising therapeutic target. Experiments suggest the capsid must be flexible to function; however, capsid structure and dynamics have not been thoroughly characterized in the absence of icosahedral symmetry constraints. Here, all-atom molecular dynamics sim...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Hadden, Jodi A, Perilla, Juan R, Schlicksup, Christopher John, Venkatakrishnan, Balasubramanian, Zlotnick, Adam, Schulten, Klaus
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927769/
https://ncbi.nlm.nih.gov/pubmed/29708495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32478
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