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Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca(2+) Influx to Assess the Role of Potassium Channels on β-Cell Function
Stimulus-secretion coupling in pancreatic β-cells requires Ca(2+) influx through voltage-dependent Ca(2+) channels, whose activity is controlled by the plasma membrane potential (V(m)). Here, we present a method of measuring fluctuations in the β-cell V(m) and Ca(2+) influx simultaneously, which pro...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927608/ https://ncbi.nlm.nih.gov/pubmed/29058185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7362-0_7 |
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